Psilohuasca: The Serpent and the Starflower A Heart Opening Sacrament of spiritual Vision, and Awakening
- Renee Boje
- Jun 30
- 9 min read

Beloved Children of the Earth Moon and Stars, Wanderers and seekers of realms seen and unseen -
There is a star-kissed mushroom, a sacred vine and a magical seed whose marriage opens a gateway into the temple of our own divine soul. This union is called Psilohuasca - a sacrament woven from the threads of ancient rainforest wisdom and cosmic mycelial intelligence. (Mycelial refers to the interconnected web-like structure of fungi.)
A Sacred Right/Rite Under Siege: The War on Plant Spirit Medicines
The war against plant spirit medicine is not merely a war against leaves and vines, roots, cacti and spores - it is a war against remembrance. A war against the flowering of consciousness, the rewilding of the spirit, and the awakening of the divine feminine and divine masculine codes that live within each of us.
For centuries, the stewards of the empire have feared the sovereign souls, the free thinkers and those with liberated spirits. They have outlawed many of the sacraments that open the heart, silence the ego, and dissolve the illusion of separation. This war is woven into colonial conquest, patriarchy, and the suppression of the sacred feminine & of Mother Nature, herself. It seeks to sever the ancient bond between humans and Mother Earth, the ancient wisdom of the Priestesses and her Plant Queendom and the sacred connection between the seeker and Source.
Today, we feel the effects of this ongoing spiritual warfare. For example, Ayahuasca - once flowing freely into the hands of devoted facilitators and ceremonial seekers here in Canada and the United States - has, in just the past year of 2025, become nearly impossible to receive. Borders are being ordered to seize all ayahuasca. Shipments are vanishing, permissions are being revoked, and those who carry the wisdom of this Master Plant Teacher are being targeted, arrested, imprisoned or silenced.
And yet - the plant spirit medicine path is resilient. The spirit of the plants cannot be destroyed. And the Light will prevail.
In the face of restriction, many plant spirit medicine facilitators have been called to adapt - guided by the whispers of Mother Earth herself to seek new allies, new combinations, new ceremonies that honor the same holy purpose: healing, remembrance, and awakening.
And so, from the fertile crossroads of tradition and transformation, Psilohuasca has emerged.

This sacrament - born from the sacred union of psilocybin mushrooms and MAO-inhibiting plants such as Banisteriopsis caapi (one of the components of traditional ayahuasca brews) or Syrian Rue Seed - offers a luminous alternative, a powerful yet gentle path for those of us seeking deep healing and spiritual communion.
Psilohuasca is not a substitute. She is her own divine intelligence, her own mythos. And yet, in this time of spiritual drought and cultural forgetting, she arrives like rain on the parched earth - an accessible, potent, and holy offering for those of us called to walk the sacred path of plant spirit medicine.
To sit in ceremony with Psilohuasca is to reclaim our birthright - to pray with Mother Earth, to see with our souls, to listen with our hearts, and to remember that our bodies are temples woven from her stardust and soil.
Psilohuasca is the alchemical blending of Psilocybin-containing mushrooms and an MAO-inhibiting plant, such as Banisteriopsis caapi or harmala-rich allies like Syrian Rue Seed (Peganum harmala). Together, these two spirit medicines entwine like two lovers in divine union, extending the visionary journey and deepening the heart’s capacity to feel, to heal, and to remember.
🤍 The Sacred Heart Awakens 🤍 At the heart of Psilohuasca lies the opening of the Anahata—the sacred heart center. As the psilocybin begins to sing its song within our blood, and the vine or rue holds space for us in their expansive embrace, many often experience a flood of compassion, forgiveness, and feelings of profound Love that cradle like the waves of the sea in the womb of the Great Ocean Mother. The walls we have built to survive begin to soften. Tears of release often begin to flow - not from sadness alone, but from the grace of finally feeling again from a place deep within from our own divine essence.
The sacred mushroom, known by many names across time and throughout many cultures - Teonanácatl, the flesh of the gods, the star-born fruit of the mycelial web - offers more than just vision. She brings healing to our hearts, soothing the aching wounds of abandonment, betrayal, and loss. Psilocybin has shown the power to dissolve the illusion of separation, helping the heart remember its own divine union with all. As fear melts in her luminous embrace, what remains is only Love - boundless, radiant, and wise.
As the mushroom’s spirit unfurls, psilocybin is gently transformed within the body into psilocin - the activated essence, the glowing blue flame of the sacrament. It is psilocin who dances across the synapses, unlocking the doors of perception and awakening the soul’s remembrance of its wholeness. In the presence of an MAO inhibitor such as caapi or rue, this conversion is potentiated and sustained, allowing the inner realms to open more fully and gracefully.
Psilocin is the sacred emissary who brings the mystical into the material. She binds to serotonin receptors in the brain, not only evoking visions but nurturing profound healing: softening depression, easing anxiety, and breaking cycles of trauma embedded deep within the nervous system. She enhances neuroplasticity, rewiring outdated mental loops and creating new bridges between thought and intuition, logic and feeling, self and Source.
While psilocybin initiates the journey, it is psilocin who walks you through the temple doors. She guides us into communion with the divine spark within and without, illuminating what longs to be seen, held, and transmuted. In her embrace, time loosens, the veil thins, and sacred remembrance arises. Spiritually, psilocin is a whisper of the Gods and Goddesses - fluid, intuitive, cosmic, and compassionate.
Psilocybin mushrooms are now being recognized by modern science for their powerful anti-depressant effects, offering hope and relief for those who have struggled in the shadows of depression, anxiety, and trauma. Clinical research has shown that even a single guided journey can lead to long-term improvements in mood, purpose, and emotional resilience. Spiritually, she is a balm for the weary soul, guiding us gently back into union with all that is sacred.
In the temple of this medicine, we are not asked to fix ourselves, but to witness ourselves with tenderness, to allow the garden of our being to bloom in its own divine timing.
The Eyes of the Soul are designed to Open
With gentle reverence and sometimes rapturous intensity, Psilohuasca can open our third eye, unveiling visions of archetypal beauty, divine geometry, ancestral messages, and cosmic remembrance. The mycelial intelligence of the sacred mushroom travels through the synapses of our spirit, while the MAO inhibitor slows time and deepens our presence, allowing our visions to expand and evolve with grace.
Many seekers describe encounters with spirit guides, elemental beings, plant deities, and even the presence of the Divine Mother and Father, shapeshifting through vine and spore to whisper the truths we are ready to receive.

The Spirit of Banisteriopsis Caapi Root Bark
Among all the sacred allies of the rainforest, none is more revered than Banisteriopsis caapi - the vine of the soul, the Grandmother of the Amazon, the living ladder between Mother Earth and the Heavenly Realms. Traditionally used in Ayahuasca brews by the Yawanawa, Shipibo, Quechua, and many other Indigenous nations, caapi root bark carries the spirit of deep purification, ancestral wisdom, and communion with the divine.
Caapi contains powerful harmala alkaloids - especially harmine and tetrahydroharmine - which act as natural MAO inhibitors, allowing psilocybin’s sacred visions to unfurl more slowly and luminously across our inner landscape. But she brings more than biochemical support, she brings deep spiritual presence and support.
The spirit of the caapi root bark is feminine, deeply maternal, and fiercely loving. She holds us through the storm, whispering songs of ancient jungle memory, guiding us gently through grief, truth, and ecstatic rebirth. Her energy is that of the cosmic womb - both death and new life. When journeyed with respectfully, she offers profound insight into generational trauma, soul contracts, and spiritual purpose.
Physically, caapi root bark has been studied for its neuroprotective, antidepressant, and anti-addictive properties. Spiritually, she is said to awaken the kundalini serpent, stir the dreambody, and open the energetic pathways to divine remembrance.
With psilocybin as her star-dancer and caapi as the grounding vine, the Psilohuasca experience becomes a holy weaving of Earth and Sky, Shadow and Light, Body and Spirit.
The Blessings of Syrian Rue
Though Banisteriopsis caapi is the vine most traditionally associated with ayahuasca, Syrian Rue - an ancient, flowering herb of the desert - has long been revered in mystical and magical traditions across Persia, the Middle East, and the Mediterranean.
Rich in harmine, harmaline, and harmalol, Syrian Rue opens the gates of perception in her own unique way. Her spirit is fiery, protective, and deeply introspective, guiding us into shadow realms and inner sanctums that often remain hidden beneath daily awareness. While Caapi is often described as maternal and nurturing, Syrian Rue is more like the Wise Crone or Desert Witch, offering fierce insight, psychic depth, and sacred boundaries.
When paired with psilocybin, Syrian Rue helps to amplify the mushroom’s visionary effects, deepen emotional awareness, and prolong the journey, often inducing powerful dream-like visions and spontaneous spiritual downloads. She is known for her mood-elevating qualities, her ability to disrupt negative mental patterns, and even for helping some seekers release the trauma held deep within their nervous system.
In traditional medicine, Syrian Rue has been used for centuries to ward off evil spirits, cleanse the aura, and protect the soul. Modern studies suggest she may also have neuroprotective, anti-inflammatory, antidepressant, and anti-anxiety effects when used with reverence and proper dosage.
A Bridge Between Science & Spirit
Though born from intuition, Psilohuasca is now being explored by modern science. Research on its components—psilocybin and harmala alkaloids—has shown promising results in alleviating depression, PTSD, addiction, and anxiety. The extended duration and emotional depth offered by this union may allow for deeper integration and more profound therapeutic breakthroughs than psilocybin alone.
Recent studies from respected institutions confirm what priestesses and shamans have long known: that these sacraments can catalyze mystical experiences with lasting emotional and spiritual benefit. Participants frequently report a sense of oneness, interconnectedness, and inner peace long after the medicine has left their system.

Sacred Use and Divine Intention
As with all entheogenic sacraments, Psilohuasca should be approached with ritual, reverence, and responsibility. This is not a casual gateway, but a portal into the deep divine feminine and divine masculine mysteries of our soul. She calls us to prepare her with intention - through prayer, cleansing, DIETA’s, and humility, and to integrate what is received from her with care.
In this sacred journey, you may meet your inner child, the God or Goddess within, and the cosmic serpent that winds through all of creation. You may be asked to let go, to feel what you have avoided, to remember who you were before the world encouraged you to forget.
And through our communion with this holy sacrament - love will lead each and every one of us home. Love heals all & Love is the key to the Gates of the Heavenly Realms.
-Written with Love & Devotion by Renee Boje
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